Roshni Kulkarni, M.D.
Office Address: Michigan State University
Department of Pediatrics and Human Development
B-220 Clinical Center
138 Service Road
East Lansing, MI 48824-1313
(517) 355-5039
Citizenship: U.S.
Present Position: Professor, Department of Pediatrics and Human Development
Director, Pediatric & Adolescent Hematology/Oncology
College of Human Medicine
Michigan State University
Education:
l973 - l975Pediatric Hematology/Oncology Fellowship, Children's Hospital of Michigan and Wayne State University School of Medicine, Detroit, Michigan
l97l - l973Pediatric Residency, Children's Hospital of Michigan and Wayne State University School of Medicine, Detroit, Michigan
l970 - l97lPediatric Residency, Osmania University, Nilofer Hospital, Hyderabad, India
l969 - l970Internship, St. Luke’s Hospital, Denver, Colorado
l968 - l969Internship, Osmania General Hospital, Hyderabad, India
l963 - l968M.D. Degree, Osmania Medical College, Indian Institute of Medical Sciences, Hyderabad India
Professional Appointments:
1992 - Present Professor, Pediatric Hematology/Oncology, Pediatrics and Human Development, present Michigan State University, College of Human Medicine.
Division Chief, Pediatric and Adolescent Hematology/Oncology
Medical Director (Pediatrics) Michigan State University Center for Bleeding and Clotting Disorders
l984 - 1992Associate Professor, Pediatric Hematology/Oncology, Pediatrics and Human Development, Michigan State University, College of Human Medicine.
l977 - l984Assistant Professor, Pediatric Hematology/Oncology, Pediatrics and Human Development, Michigan State University, College of Human Medicine.
l977 - l978Assistant Director, American Red Cross, Lansing, Michigan
l976 - l977Assistant Director of Staff, American Red Cross, Children's Hospital of Michigan, Detroit, MI.
l975 - l976Assistant Professor of Hematology, Niloufer Hospital, Institute of Child Health, Hyderabad, India
Career Development:
1996Hemophilia Treatment in the Age of Genetic Engineering. Bayer Corporation. San Francisco. California, Nov. 1996.
1991AAMC Women in Medicine Professional Development Seminar
1989Michigan State University, Primary Care Faculty Development
1987Georgetown University, Intensive Bioethics course XIII
Certification:
Diplomate of American Subspecialty Board, Pediatric Hematology/Oncology, December l978
Diplomate of American Board of Pediatrics, July, l975
FLEX -- Michigan, September l975.
American Medical Qualification Examination, E.C.F.M.G., Number l08-728-7, February l2, l969.
Honors and Citations:
East meets West: Profile of Roshni Kulkarni. . HEMAware, 7. (6) 2002.
Cited in Hemalog article on “Head trauma in Hemophilia”. 2002
The William B. Weil, Jr. M.D., FAAP Endowed Distinguished Pediatric Faculty Award, April 1999
Alpha Omega Alpha Honor Medical Society (AOA), MSU Gamma Chapter, November 1998
Awarded Certificate for Excellence in Teaching, 1996 (MSU/EWSH Pediatric Residency Program)
Awarded Certificate for Excellence in Teaching, 1993 (MSU/EWSH Pediatric Residency Program)
Michigan State University, College of Human Medicine Distinguished Clinician Award, May, 1991
Awarded Certificate for Excellence in Teaching, l987 (GMEI Residency Training)
Awarded Certificate for Excellence in Teaching by pediatric residents, 1980 (GMEI)
Cited in a book called “They Accepted the Challenge” by Kuntzleman CT and Cryderman L. St. Martin’s Press, New York, NY 10010, 1980
Awarded Certificate by Institute of Child Health, Niloufer Hospital, Hyderabad, India, in recognition of outstanding contribution to the welfare of women and children, July, l979
Volunteer Services
1997Mentor for minority freshman, Michigan State University
1997-1998India Cultural Association volunteer at Everett High School- teach students science on Saturday mornings.
Memberships:
International Society of Thrombosis and Hemostasis
Michigan Society of Hematology Oncology
World Federation of Hemophilia
National Hemophilia Foundation
Hemophilia Research Society
American Society of Pediatric Hematology/Oncology, l98l to present.
Central Michigan Pediatric Society, l98l to 1982.
American Society of Hematology, l980 to present.
Michigan State Medical Society, l978 to 1979.
American Academy of Pediatrics, l970 to 1989
Michigan State University Cancer Consortium, 1989 to present.
Medical Advisory Boards:
2002 — PresentAventis-Behring Corporation
2002 — PresentBaxter Corporation. North American Clinicians Advisory committee
2002 — PresentSpeakers Bureau NovoNordisk Corporation
1999 — PresentMedical & Scientific Advisory Committee, National Hemophilia Foundation, Midwest representative
1993 - 1996Medical & Scientific Advisory Committee, National Hemophilia Foundation, Region 10 Representative
l980 - PresentHemophilia Foundation of Michigan
1988 - PresentMichigan Department of Public Health, Pediatric Subspecialty Advisory Board
1992 - 1995Chair, Medical Advisory Board, Hemophilia Foundation of Michigan
1994 - 1997Medical Director, Special Days Camp for children with cancer
1991 - 1992Co-Chair, Medical Advisory Board, Hemophilia Foundation of Michigan
1989 - 1990Children's Leukemia Foundation of Michigan
1986 - 1990Children's Leukemia Foundation of Michigan
l979 - l982Children's Leukemia Foundation of Michigan
l978 - 1989American Red Cross, Lansing Chapter
Board member:
2002 — Present Elected to the Hemophilia Research Society
1989 - PresentSpecial Days Camp for Children with Cancer
1988 — 1993Children's Leukemia Foundation of Michigan
1980 - 1982Hemophilia Foundation of Michigan
Committees
University Committees
2001 - Admissions Committee, College of Human Medicine
1999 - 2001International Studies/Programs
2000Grievance committee
2000 — PresentMichigan Partnership for the Advancement of End-of-Life care curriculum committee
1995 -1999Cancer Core Grant Committee
1995 - 1999University Committees on Academic Council/Faculty Council
1994 - PresentDepartment Representative, Clinician's Council, and Michigan State University
1990 - 1992Women's Advisory Committee to the Dean
1988 - 1990Credentials/Privileges Committee, Clinical Center, Michigan State University
1979 - 1980Search committee for Department Chairperson, Pediatrics and Human Development, Michigan State University
1979 - 1981Alternate Member for William B. Weil, Jr., M.D., on college Planning Committee, College of Human Medicine, Michigan State University
Departmental Committees
1994 - PresentExecutive committee, Dept. of Pediatrics and Human Development
1994 - PresentDivision Chief, Peds Hematology/Oncology
1994 - PresentManagement Committee
2002Grievance committee
1998 - 2001Reappointment, Promotion & Tenure Committee
1999 —2000 Neonatology search committee
1997 - 1998Chair search committee, general pediatrics.
1993 - 1996Reappointment, Promotion & Tenure Committee
1994 - 1995Pediatric Residency Task Force Committee, Department of Pediatrics/Human Development
1990 - 1993Pediatrics/Human Development, Executive Committee
1990 - 1991Associate Director, Pediatrics/Human Development, Clinical Sub-Specialty Services
1990 - 1991Pediatrics/Human Development, Residency Advisory Board
1991 - 1992MSU/E.W. Sparrow Hospital, Pediatric Strategy Committee
1988 - 1991Reappointment, Promotion & Tenure Committee
1985 - 1989Pediatric Training Committee (Residency Training)
1984 - 1985Search committee, Pediatric Residency Director, Michigan State University
1982 - 1983Pediatric Training Committee, Pediatrics and Human Development, Michigan State University
1979 - 1981Executive Committee, Pediatrics and Human Development, Michigan State University
1979 - 1985Reappointment, Promotion and Tenure Committee, Pediatrics and Human Development, Michigan State University
Hospital Committees
2001- Transfusion Committee Sparrow Hospital
1995 - 1996Pediatric Planning Committee for Pediatric outpatient clinics
1992 - 1995Executive Committee, Department of Pediatrics, Sparrow Hospital
1992 - 1993Associate Chair, Department of Pediatrics, Sparrow Hospital
1992 - 1993Board Member, Action & Advisory Committee, Sparrow Hospital
1991 - 1992Committee for Helping Children through Bereavement - Ele's Place
1986 - 1989Oncology Center Committee, E.W. Sparrow Hospital
1982 - PresentTumor Board, E.W. Sparrow Hospital, Lansing, Michigan
1978 - PresentIngham Medical Center, Pediatric Department Committees, Lansing, Michigan
1977 - 1978Transfusion Committee, St. Lawrence Hospital, Lansing, Michigan
National/Regional Committees
2002 — PresentPediatric Coagulation Consortium of the Hemophilia Research Society
2002 — Present Planning Committee, Annual meeting of the National Hemophilia Foundation
1999 - PresentMedical & Scientific Advisory Committee, National Hemophilia Foundation, Region V East representative (MI, OH, IN)
2002Data Committee, Hemophilia Foundation of Michigan
2001- Present Chair Neonatal Task force, National Hemophilia Foundation.
2001- PresentElected to the Universal Data Collection (UDC), working group committee, Center for Disease Control (CDC), Atlanta.
1996 - PresentHemophilia Research Society
2000 - PresentAdolescent and Young Adult Task Force, Children’s Oncology Group
2002 - PresentMichigan Hospice and Palliative Care Committee. Pediatric Work Group
1999 - 2002Principal investigator Children’s Oncology Group
1999 - PresentEnd of Life Task Force, Children’s Oncology Group
1999 - 2000Education and Information Committee, National Hemophilia Foundation
1998- 1999Nominating Committee, Hemophilia Research Society.
1993- 1995Medical & Scientific Advisory Committee, National Hemophilia Foundation, Region 10 Representative
1996 - PresentBlood club of Michigan
1996 - PresentMember Clinical Pathways Committee. Hemophilia Foundation of Michigan
1994 - 1995American Association of Blood Banks, Transfusion Practices committee (liaison member of the National Hemophilia Foundation)
1992 - 1995Chair, Medical Advisory Board, Hemophilia Foundation of Michigan
1994 - PresentMedical Director, Special Days Camp for children with cancer
1988 - PresentMichigan Department of Public Health, Pediatric Subspecialty Advisory Board
1988 - 1990Ethics Committee of Children's Cancer Study Group
Clinical Service:
1994 - PresentPediatric Hematology/Oncology Outreach Clinic at Marquette General Hospital, Marquette, Michigan
1997Hemophilia Clinic at Saginaw, Michigan
1996-1997Gaucher’s Disease Treatment Center (with Dr. Wilson)
1996 Cristo Rey Clinic Volunteer (Pediatrician for indigent population)
1992 - 1993Pediatric Hematology/Oncology Outreach Clinic at the Burn’s Clinic, Petoskey, Michigan
1988 - 1998Sickle Cell Foundation, designated physician for the Lansing area
1977 - PresentCo-director, Pediatric Hemophilia Comprehensive Care Clinic, MSU
1977 - PresentDirector, Pediatric Hematology/Oncology Service, MSU
1982 - 1999Regional investigator for Children's Cancer Study Group
Reviewer
1999 - PresentHaemophilia
1998 - PresentReviewer for Journal of Pediatric Hematology Oncology
2000 - PresentReviewer American Journal of Hematology
1996Abstract reviewer for National Hemophilia Foundation National meeting, San Diego, California.
1995Editorial review AABB tech manual.
1987-89Grant Reviewer for Children's Leukemia Foundation 1987, 1988, 1989, 1990
1980 & 1989Basic Research Science Grant BRSG
1992-94Grant Reviewer for Hemophilia Foundation of Michigan
1994American Cancer Society Institutional Research Grant.
Teaching Experiences:
Yearly Grand rounds at Flint, Saginaw, Lansing MI
Teach Adult hem/onc fellows and residents as well as students and family practice residents from Escanaba and Marquette MI
2002Mentor program for Year I students, clerkship rotation of 3rd and 4th year students. Nurse practitioner teaching
2001Problem based learning and clerkship student teaching
2000 — PresentMentor program, MSU CHM, pediatric clerkship, 4th year hem/onc rotation.
1998 — PresentPediatric Clerkship Student Rotation and Marquette General Hospital, pediatric hematology/oncology clinics (students from UP)
1998 — 1999Mentor program, MSU CHM, pediatric clerkship, 4th year hem/onc rotation.
1995 - 1997Mentor program, MSU CHM, pediatric clerkship, 4th year hem/onc rotation.
1994 - 1995Hematology/Neoplasia Domain Teaching, Doctor-Patient Relationships
1993 - 1994Curriculum Development Group for Hematology Neoplasia Domain
1991 - 1993Mentor Program (HM 581), Michigan State University
1989 - PresentNewborn Experience, Young Child, and Adolescent Experience.
1988 - PresentFocal Problems. Newborn Experience
1986 - 1988Focal Problems. Adolescent Experience
1986 - 1988Focal Problems. Medical Ethics
1977 - PresentFocal Problems for medical students (HM 510).
1977 - PresentClinical Science and Focused Clinical Appraisal, Michigan State University
1977 - PresentPediatric Clerkships for third and fourth year medical students.
1977 - PresentAnnual presentations to MSU Clerkship students at Grand Rapids, Flint, Saginaw and Kalamazoo campuses.
1977 - PresentActive participant in Pediatric Subspecialty Rounds (weekly).
1978 - 1980Osteopathic medicine course (OST 551) (Blood groups and blood transfusion).
1977 - 1980In-service training for nurses at Ingham Medical Center and E.W. Sparrow Hospital (childhood leukemia, blood coagulation and transfusion therapy)
1978 - 1979Pediatric Transfusion Therapy. Medical Technology Students, Michigan State University
1978 - 1979Granulocyte Transfusion Therapy, Medical Technologists and Volunteers at Lansing Red Cross
1978 - 1979Medical Students (III, IV, and final year) and pediatric residents of Osmania University. Indian Institute of Medical Science
1974 - 1975Medical Students (III and IV year) and pediatric residents, Wayne State University. (Laboratory Hematology)
Educational Brochure/videos/animations
1.“How does blood clot? Bleeding and clotting disorders: hemophilia, von Willebrand Disease and thombophilias”. A computerized animation using Flash technology. Kulkarni R, Reddy U, Evatt B. 2002.
2.Melvin JR, Horowitz RN, MacDonald D, Kulkarni R, Gannaway J. A Quality and cost effective approach for evaluating patients with possible inherited thrombophilia. Educational Brochure and CD-ROM. Sept. 2002.
3.Shapiro J, Fung E, Kulkarni R. Education Brochure entitled “Movin’ Up” Adult Healthcare. Publication intended for patients with hemophilia transferring from pediatric to adult healthcare and available through the National Hemophilia Foundation at 1-800-42-HANDI. Brochure made possible by an educational grant from Aventis Behring. 2000.
2.Worked with Dr. Robert Janco, Vanderbilt University, on revising and updating the “STANDARDS AND CRITERIA FOR THE CARE OF PERSONS WITH CONGENITAL BLEEDING DISORDERS”. Document published by the National Hemophilia Foundation MASAC in 2001.
3.Educational brochure on protein C and S deficiency for the MSU Comprehensive Center for bleeding and clotting disorders.
4."My Friend has Leukemia." Educational videotape. American Cancer Society.
5.Participant in “The Dying Child- how to tell a child”. Human Development course video. E. Seagull.
Grants/studies:
1.Women with bleeding disorder: a pilot study. CDC grant. 2002.
2.Integration of Thrombotic Disorders into Hemophilia Comprehensive Treatment Centers: Michigan Collaborative Prevention Pilot. CDC grant awarded (collaboration between MSU, U of M and WSU) 2002.
3.Aventis-Behring unrestricted Educational grant for developing animation of laboratory aspects of bleeding disorders and von Willebrand disease. R.Kulkarni, Connie Miller, UM Reddy, BL Evatt.
4.FENOC study: an international collaborative study of comparison of FEIBA and NovoSeven.
5.Study of safety and efficacy of antihemophilic factor/von willebrand factor-complex (Humate-P) using individualized dosing in pediatric and adult surgical patients with von Willebrand’s disease. Aventis-Behring 2002
6.AHF-PFM, Protein Free Recombinate Study 2000. Baxter study on new recombinant factor VIII
7.A randomized, double blind, multi-center parallel group trial comparing the safety and efficacy of IGIV-Chromatography, 10% (experimental) with IGIV-solvent detergent treated, 10% (control) in patients with Idiopathic (immune) Thrombocytopenic Purpura (ITP). Bayer Corporation.
8.Prospective randomized trial of anti-D immunoglobulin (WinRHO SDfTM) vs IVIg in the treatment of acute idiopathic thrombocytopenic purpura (ITP) in children 1999. Study with Dr. Tarantino, U of Louisville, KY.
9.Genetics of Inhibitor formation in Hemophilia. Multi-institutional study (with Joan Cox Gill, Children’s Hospital of Wisconsin).
10.Genentech, Inc. An open label single arm clinical trial of the safety and efficacy of recombinant tissue plasminogen activator (rt-TPA) for restoration of function of central venous access devices. 1999-2000.
11.Academic Achievement of Hemophiliacs 1998 — 2000.
12.A study of ADHD in Hemophiliacs. MSU, Wayne State University and University of Michigan 1999. Cascade grant with Wayne State University and University of Michigan for study of ADHD in Hemophiliacs, 1999-2000.
13.Universal Data and serum specimen collection for hemophilia. CDC. 1999, 2000.
14.National Childhood Cancer Foundation, Children’s Cancer Study Group/Children’s Oncology Group grants. 1997, 1998, 1999, 2000, 2001.
15.Cancer Center at Michigan State University, grant for support of pediatric oncology program, 1999.
16.Randomized trial of interferon and interferon with ribavirin for treatment of hepatitis C in hemophiliacs. Co-PI. 1997.
17.Obtained grant from Alpha Therapeutics for questionnaire for the study of neonatal intracranial hemorrhage 1996-97.
18.Cascade grant: Hemophilia Foundation of Michigan to establish clinic in Saginaw, Michigan, 1997.
19.Children’s Leukemia Foundation 1995. Parental caregivers of children with cancer. Co-investigator
20.Cancer Center at MSU - Cancer Center Planning Grant (NCI) 20 % time. Account 61-1158. 1996.
21.All-University Research Initiation Grant for 1994-1995.
22.The Induction of Fetal Hemoglobin (HbF) Production in patients with Sickle Cell Disease. Co-Investigator.
23.Hemophilia Comprehensive Care Grant Co-PI , Maternal Child Health Bureau (MCHB) Co-PI Center for Disease Control — Co-PI, Cascade grant for hemophilia Co PI. Safety and Efficacy of Anti-Hemophiliac (Recombinate) FVIII (rAHF) in Previously Untreated Patients. Co-RI, Baxter Pharmaceuticals, December 1993 - December 1998.
24.Alpha-nine SD Brand of Coagulation F-IX (Human) affinity purified organic solvent detergent treated; an open label study of viral safety in previously untreated individuals with hemophilia.
20.Project 175 - Randomized Double-Blinded Phase I-III Trial of Monotherapy vs Combination with Nucleoside Analogs in HIV Infected Persons with CD4 Cells more than or equal to 200 and less than or equal to 500. 1994. Co-PI
20.Orion Medical Sciences Institute, "Children's Cancer Study Group Chairman's Grant," awarded 1992 & 1993, 1994, 1995, 1996, 1997, 1998.
21.BRSG grant (PI), "Granulocyte Transfusion in Septic Newborn Puppies," 1978, awarded.
22.Children's Leukemia Foundation Grant, Co-PI with Dr. C.W. Smith, 1979, awarded.
23.Cystic Fibrosis Foundation (PI), "Leukocyte Function in Cystic Fibrosis," 1979, awarded.
24.BRSG grant (PI), "Free Erythrocyte Protoporphyrin in Patient on Chloromycetin," 1980, awarded.
25.Hemophilia Foundation of Michigan (PI), "A Comprehensive Study of Antibody Status in Patients with Hemophilia," 1989-91, awarded $19962.00/year x 2 years.
26.BRSG grant (PI), "Protein Kinase C in the Resistance of Human Tumor Cells to Anticancer Drugs," 1990, awarded.
Participation in Studies:
1.Developed Universal Data collection forms for babies with bleeding disorders.
2.Childrens Oncology Group Trials.
3.Treatment of children with Diamond Blackfan Anemia with high dose methylprednisolone- participant.
4.Immunologic and genetic parameters associated with inhibitor development in previously untreated patients with severe hemophilia and on Kogenate. Regional investigator 1995 - present.
5.A randomized prospective study for the prevention of joint disease in children with Factor VIII deficiency, Opened April 1996.
6.Children's Cancer Study Group, placement of children with cancer on therapeutic clinical trials.
7.Recombinant Factor VIII for the Treatment of Previously Untreated patients with Hemophilia A - Safety, Efficacy and Development of Inhibitors. J.M. Lusher, S. Arkin, C.F. Abildgaard, R.S. Schwartz and the Kogenate Previously Untreated Patient Study Group. NEJM 328:453, 1993.
8.A Multicenter Study of Recombinate Factor VIII (Recombinate): Safety, Efficacy and Inhibitor Risk in Previously Untreated Patients with Hemophilia A. G.L. Bray, E.D. Gomperts, et al., and the Recombinant Study Group. Blood 83(9): 2428-2435, 1994.
9.Induction of Immune Tolerance in Infants and Children with Hemophilia A and High Responding Inhibitors. A Prospective Study of the Short Term Cost and Effectiveness. Regional RI.
10.The Psychological Impact of HIV Positivity on the Hemophiliac Child and his Family. Co-PI.
Public and Community Service Presentations:
1."Childhood Leukemias: Impact on the Family." Lansing Community College, Lansing, Michigan. Death and Dying Course, Professor, Ray Riskey. 1979.
2."Childhood Leukemias." Children's Leukemia Foundation, Lansing Chapter, Lansing, Michigan, May 7, 1979.
3."Childhood Leukemia with Reference to a Patient: Susan Guild." Interview by CBS-TV. 1980.
4."Childhood Cancers." American Cancer Society, Mason, Michigan.
5."Childhood Leukemias." WKAR Radio, Michigan State University, East Lansing, Michigan. September, 1980.
6."Childhood Leukemias." American Cancer Society, E.W. Sparrow Hospital, Lansing, Michigan. October, 1981.
7."Childhood Leukemia" Interviewed by P.M. Magazine (Syndicated T.V.)
8."Bleeding Problems in the Newborn." American Medical Technologists and American Society for Medical Technology Regional Meeting. 1982.
9."The Use of Relaxation and Imagery in Children with Leukemia: An Easier Way." Annual Meeting of the Children's Leukemia Foundation, Michigan Division, Kalamazoo, Michigan, June, 1984.
10."Neonatal Bleeding Disorders." Region IV of the American Society for Medical Technology. September 27-29, 1984.
11."Terminal Illness in Children." Interview by WJIM-TV, Lansing, Michigan, February, 1987.
12.Presentation at the first Annual Career Night for students who participate in the Mathematics Science Technology at Michigan State University (MST at MSU), July 26, 1996.
13.“Where and what treatments are available for childhood cancer”. Column on House Calls, Lansing State Journal. May 1, 1995.
14.Expert Panel for Children’s Miracle Network. 1993, 1994,1995.
15.Presentation to Michigan Association of Physicians From India (MAPI), Lansing chapter regarding corporate sponsorship of Special Days Camp for children with Cancer. Obtained $700 for camp activities, 1996.
16.Math, Science and Technology in Medicine: Presentation at the second Annual Career Night for students who participate in the Mathematics Science Technology at Michigan State University (MST at MSU), July 1997.
17.The Adolescent Gap in Cancer. Lansing State Journal, Ingham County Medical Society supplement. 1997.
18.Participant speaker at the Mid-Michigan’s third National Cancer Survivors Day Event. June 1997.
19.Springfest meeting of Hemophilia Foundation of Michigan, Dearborn MI. May 1997. Factor VIII inhibitors, diagnosis and treatment. (invited speaker).
20.Springfest meeting of the Hemophilia Foundation of Michigan. Dearborn MI. Coagulation 101. R. Kulkarni. May 30, 1998.
21.Keynote speaker, 1999 annual meeting American Red Cross Great Lakes Blood Services Region. Talk entitled “Blood: the gift of life. Kellogg Center. East Lansing June 22, 1999.
22.Sparrow Hospital Outreach Program, Michigan Athletic Club. “Sickle Cell Anemia”, February 4, 2000.
23.Springfest meeting of the Hemophilia Foundation of Michigan. Dearborn MI. ADHD and Hemophilia. Troy MI. R. Kulkarni. May 5, 2001.
24.Cited in HemAware, June 2001, pages 12-19.
25.Shapiro J; Fung E; Kulkarni R. Education Brochure entitled “Movin’ Up” Adult Healthcare. Publication intended for patients with hemophilia transferring from pediatric to adult healthcare. Available through the National Hemophilia Foundation at 1-800-42-HANDI. Brochure made possible by an educational grant from Aventis Behring. 2000.
26.Inhibitors in hemophilia. Hemophilia Federation of America. Cleveland. April 12, 2002
27.Gene therapy for hemophilia. Region I and region III meeting. New York. April 28, 2002.
28.Clinical Research: a Bond between Community Hospitals and University. Invited presentation to representatives of Pfizer pharmaceutical at the request of the Office of the Vice President for Research, Michigan State University.
.
Presentation to the Medical Community:
1.Physiology of Coagulation. Coagulation Symposium, Ingham Medical Center, Lansing, Michigan. October 28, 1977.
2.Granulocyte Transfusion. Blood Bank Staff, University of Michigan. 1977.
3.Hematology/Oncology in Third World Countries. University of Minnesota. 1977.
4.Acute Leukemia in Children. Michigan Chapter of American Academy of Pediatrics, Boyne Mountain, Michigan. 1978.
5.Anemia in Childhood. Family Practice Seminar. E.W. Sparrow Hospital, Lansing, Michigan. August 30, 1978.
6.Cancer -- Its Psycho Social Economic Impact. St. Lawrence Hospital, Lansing, Michigan. April 25, 1979.
7.Bleeding Problems as They Present in the Emergency Room. for E.R. Physicians at Ingham Medical Center, Lansing, Michigan. October 19, 1979.
8.Neuroblastoma. Surgical Grand Rounds, Ingham Medical Center, Lansing, Michigan. December, 1980.
9.Dropping Platelets in the Newborn. Neonatology and Perinatology Conference, E.W. Sparrow Hospital, Lansing, Michigan, November, 1980.
10.Cancer in the Pediatric Age Group -- Brain Tumors, Leukemia, etc. Presented at a conference on Current Concepts in Cancer and Oncology. Flint, Michigan. May, 1981.
11.Cancer in the Young. Presented at, Cancer: Its Impact on You. E.W. Sparrow Hospital. May, 1981.
12.Support for Families. Panel Discussion, Second Annual Leukemia Symposium of the Children's Leukemia Foundation of Michigan, Michigan State University, East Lansing, Michigan. July 11, 1981.
13.Assessment on Immune Thrombocytopenic Purpura. Presented at a conference on Blood Coagulation: Clinical and Laboratory Aspects. Michigan State University. September, 1983.
14.Hypnosis, Imagery, and Relaxation in the Practice of Pediatrics. Noll, R.B.; Kulkarni, R.; Solomon, R. Presentation at Pediatric Grand Rounds, Detroit Children's Hospital, Detroit, Michigan. October, 1984.
15.Long-Term Follow-Up of Language and Cognitive Development of Three Brothers with Mannosidosis. Noll, R.B., Kulkarni, R., Netzloff, M.L. Paper presented at the Annual Meeting of the International Neuropsychological Society, San Diego, California. February, 1985.
16.Ethical Dilemmas in Pediatric Oncology. Noll, R.B.; Kulkarni, R. Presentation at the Department of Psychology, Michigan State University ethics seminar, Lansing, Michigan. May, 1986.
17.Integration of Mental Health Services in the Pediatric Oncology Service: Clinical and Research Opportunities. Noll, R.B., Kulkarni, R. Presentation at the bi-annual meeting for the Children's Cancer Study Group, Atlanta, Georgia. April, 1986.
18.Overview of the Disease Process: Acute Childhood Leukemia. Kulkarni, R. Course presented to Michigan Pharmacists Association/Michigan Society of Hospital Pharmacists, Interim Meeting. Dearborn, Michigan. March 6-8, 1987.
19.Indications for Infusion of Blood Components: Changes in the 80's. Swisher, S.N.; Schwartz, K.; Penner, J.; Kulkarni, R.; Shafer, A.W. course presented to Michigan State Medical Society, 1987 Annual Scientific Meeting. Dearborn, Michigan. November, 1987.
20.Presentation to the United Way regarding importance of research in Leukemia. November, 1987 and 1988.
21.Cancer in Children: The Impact on the Child and the Family from Multiple Perspectives. Noll, R.B., Kulkarni, R., Netzloff, M.L. Presented in San Diego, California, 1988.
22.Adriamycin Efflux of MCF-7 Resistant and Sensitive Cell Lines. Presentation to Plant Biology Laboratory, MSU, October 1990.
23.Effect of Verapamil on Adriamycin Efflux of MCF-7 Resistant and Sensitive Cell Lines. Presented at the Oncology Seminar, Department of Medicine, MSU, November 1990.
24.Decreased Efflux of Adriamycin by Verapamil in Adriamycin Resistant MCF- Human Breast Tumor Cells: A Laser Cytometric Analysis. Kulkarni, R., Madhukar, B.V., Chang, C.C., Trosko, J.E., Dimitrov, N., Jou, Y.S., Jiwa, A., Charmella, L. American Cancer Society 1991 Research Conference, Detroit, MI, September 20, 1991.
25.Increased Retention of Adriamycin by a Protein Kinase C Inhibitor, Calphostin C in Resistant MCF-7 Human Breast Tumor Cells. R. Kulkarni, B.V. Madhukar, H. Rupp, C. Chang, J.E. Trosko, L. Charmella, N. Dimitrov. The Ohio Valley-Lake Erie Association of Cancer Centers (OLACC) Meeting, September 11, 1992.
26.Drug Resistance in Cancer Cells. Presented to the Michigan Cancer Consortium, October 1992.
27.DIC and Gram Negative Sepsis. Medicine Grand Rounds, Hurley Hospital, Flint, Michigan, 1993.
28.Septic Shock in Children. Presentation to ER Physicians, E.W. Sparrow Hospital, Lansing, Michigan, 1993.
29.Brain Tumors in Children. Neurosurgery Rounds, E.W. Sparrow Hospital, Lansing, Michigan.1994
30.The Science and Politics of Women's Health in America. Wayne State University School of Medicine, The Westin Hotel, Detroit, Michigan, May 12, 1993.
31.Hemophilia: Past, Present and Future. Kulkarni, R. Invited Presentation for the Michigan Academy of Pediatric Dentistry Winter Meeting, Hotel Baronette, Novi, Michigan, March 5, 1994.
32.Current Issues in Hemophilia. R. Kulkarni. Presentation at the Region V Meeting and Provider Retreat, National Hemophilia Foundation, South Bend, Indiana, September 1994
33.Career Development of Women in Academic Medicine. Presentation to the Primary Care Faculty Development Fellows, Michigan State University, June 7, 1994.
34.Cranial Hemorrhages in neonatal hemophilia . Region V-East Hemophilia Treatment Center Meeting. Provider retreat, Ohio. Sept. 13, 1995.
35. New Strategies in the Diagnosis and treatment of Acute Childhood Leukemia. Presented at the Adult Hematology/ Oncology Conference. MSU. Sept. 1995.
36.Cranial Hemorrhages in neonatal hemophilia. Marquette General Hospital Physician and nursing conference. Nov.1995.
37.Cranial Hemorrhages in Neonatal Hemophilia. Medical and Scientific Advisory Committee (MASAC), National Hemophilia Foundation, Philadelphia Oct.14, 1995.
38.Acute lymphoblastic leukemias in children. R. Kulkarni. presentation to the epidemiology research group. 1996.
39.The Adolescent Gap and issues in Pediatric cancer. Cancer Committee. Sparrow Hospital, Sept. 1996.
40.Meeting the Challenges of Pediatric Hematology and Oncology. R. Kulkarni. Fifth Annual Outreach Conference. Sparrow Regional Childrens Center. Marriott University Place. East Lansing. Oct. 15, 1996.
41.Stress management for resident physicians. Sparrow Hospital, Oct. 30, 1997 Panel member. Coordinator Dr. J Brady.
42.Current practices regarding neonatal intracranial hemorrhage and obstetrical care and mode of delivery of pregnant hemophilia carriers. Medical and Scientific Advisory Committee (MASAC) National Hemophilia Foundation, New Orleans, Nov. 1997.
43.National Hemophilia Foundation Medical and Scientific Advisory Committee (MASAC): Recommendations regarding neonatal intracranial hemorrhage and deliveries, New Orleans, Nov. 1997.
44.Quality of life issues for cancer patients and their families. Children’s Leukemia Foundation. Detroit Michigan, April 22, 1998.
45.Inhibitor meeting. Invited participant, Nabi Pharmaceuticals, summer 1998.
46.Meeting today’s needs… Facing tomorrow’s challenges. Midwest Bleeding Disorders Conference. September 17-18, 1998. Chicago, IL. Co-chair, physicians discussion group.
47.Shortages of clotting factors. Invited participant, Centeon Laboratories. Chicago, IL, September 9, 1998.
48.Acute Lymphoblastic Leukemia in Children. Invited Speaker. Pediatric/Perinatal Update. Marquette, MI. September 25, 1998.
49.Adolescent and Childhood Leukemias. Department of Internal Medicine, Hematology/ Oncology Division, October 23, 1998.
50.Acute Lymphoblastic Leukemia in Children and Adolescents. Department of Family Practice, November, 1998.
51.Intracranial Hemorrhage in Newborn with Hemophilia: Prevention, Recognition, Management and Neonatal Care. Conference on Women with Bleeding Disorders. New York, March 19, 1999 (Invited Speaker).
52.New Research: Current Hemophilia Research. Presentation. The future of hemophilia care: preparing for the 21st century. 1999 Region V-east meeting. Sept. 1999. Newbury, Ohio.
53.Intracranial Hemorrhage. Pre-, peri-, Neonatal issues in the management of infants with bleeding disorders. 1999 National Hemophilia Foundation Symposium. Management of the neonate. Nov. 4-6 Dallas, Texas.
54.Neonatal Hemophilia. Invited speaker. Grand rounds presentation. Medical College of Ohio, Toledo, Ohio. Oct. 11, 2000.
55.Perinatal issues in hemophilia. Invited speaker. Ob-gyn Grand rounds. Sparrow hospital. Oct. 17, 2000.
56.Prenatal, perinatal and neonatal issues in hemophilia. Invited speaker. CDC Atlanta. Oct. 23, 2000.
57.Perinatal issues in newborns with hemophilia. Region 1 meeting. Salem, MA. April 27, 2001.
58.The Hemophilia Expert Panel meeting on the cost effectiveness of care of hemophilia with inhibitors, July 9, 2001. Hotel Le Meridien Etoile in Paris, 81 Boulevard Gouvion Saint-Cyr, Paris, France.
59.Neonatal alloimmune thrombocytopenia. Invited speaker. Neonatology conference. Sparrow Hospital. Aug. 28. 2001.
60.Head trauma in hemophilia; a hematologist approach. Invited speaker. The 53rd Annual meeting. National Hemophilia foundation. Nov. 16th, 2001.
61.Infectious complications of central venous catheters in hemophilia" Round table on prophylaxis and unsolved problems in prophylaxis. Rome Italy, Saturday April 20, 2002.
62.Inhibitors in hemophilia. Hemophilia Federation of America. Cleveland. April 12, 2002
63.Hot topics in hemophilia. Gene therapy and inhibitors. Region I and III meeting. New York. April 28, 2002
64.Animation of “How does blood Clot and von Willebrand Disease” Regional Hemophilia meeting. Fort Wayne. Indiana. 2002
65.Animation of “How does blood Clot and von Willebrand Disease” Medical and Scientific Advisory Committee Meeting. National Hemophilia Foundation, Orlando Nov. 2002.
66.Use of recombinant Factor VIIa in pediatric liver trauma. Case presentation and animation of the physiology of blood clotting. Selected for presentation at the rFVIIa innovators conference. Scottsdale AZ. Dec 2002
Publications:
1.Iyer, R., Ravindranath, Y., Kulkarni, R., Philippart, A., Reed, J.O., Brough, A. J., Zuelzer, W.W.: Bilateral Interstitial Pneumonia in Acute Lymphoblastic Leukemia. Am. J. Hematology 1:225-235, 1976.
2.Kulkarni, R., Rao, V.K.M., Bopardikar, K.R.: A Study of Leukemia. Indian Pediatrics, Vol. XIV, No. 2, February 1977.
3.Kulkarni, R., Bailie, M.D., Bernstein, J., Newton, B.: Progression of Nephroblastomatosis to Wilms Tumor. J. Pediatrics, 96:1:178, January 1980.
4.Kulkarni, R.: Report presented to the Government of India of the "Need for Establishment of a Department of Hematology in Niloufer Hospital.: Hyderabad, India, 1981.
5.Kulkarni, R., Murray, D.L., Gupta, S., deMendonca, W.C., Leader, I.: Multiple Splenic Aspergillomas in a Patient with Acute Lymphoblastic Leukemia. American Journal of Pediatric Hematology/Oncology, 4(2):141-145, 1982.
6.Kulkarni, R., Netzloff, M.L., Texiera, C.: Familial Cryptochidism and Testicular Tumors in Non-Twin Brothers. Annals of Clinical and Laboratory Science, 13(4): 327-331, 1983.
7.Noll, R.B., Kulkarni, R.: Complex Visual Hallucinations and Cyclosporine. Archives of Neurology, 41:329, 1984.
8.Noll, R.B., Kulkarni, R., Netzloff, M.L.: Follow-Up Language and Cognitive Development in Three Brothers with Mannosidosis. Archives of Neurology, 43:157-159, 1986.
9.O'Malley, D.P., Cousineau, A.J., Kulkarni, R., Higgins, J.V.: Double Minute Chromosomes: A Bone Marrow Indicator of Neuroblastoma Metastasis and Relapse: Two Case Reports. Cancer, 57(11):2158-2161, 1986.
10.O'Malley, D.P., Kulkarni, R., Oaks, M.K., Higgins, J.V.: Acute Lymphoblastic Leukemia with a Unique Rearrangement between Chromosomes 4 and 11. Cancer Genetics and Cytogenetics, 31:291-294, 1988.
11.Kumar, A., Brar, S.S., Murray, D.L., Leader, Il, Gera, R., Kulkarni, R.: Central Venous Catheter Infections in Pediatric Patients--In a Community Hospital. Infection, 16:86-90, 1988.
12.Noll, R.B., Kulkarni, R.: Cognitive and Motor Development of Infants Coping with Cancer: Longitudinal Observations. Infant Mental Health Journal, 10(4):252-262, 1989.
13.My Friend has Leukemia. Educational Video Tape for the American Cancer Society.
14.Noll, R.B., Netzloff, M.L., Kulkarni, R.: Long Term Follow-up on Biochemical and Cognitive Functioning in Patients with Mannosidosis. Archives of Neurology, 46:507-509, 1989.
15.Moore, J.B., Kulkarni, R., Crutcher, D.C., Bhimani, S.: MRI in Multifocal Eosinophilic Granuloma. Staging Disease and Monitoring Response to Therapy. American Journal of Pediatric Hematology/Oncology, 11(2):174-177 1989.
16.Noll, R.B., Bukowski, W.M., Rogosch, F.A., LeRoy, S.S., Kulkarni, R.: Social Interactions between Children with Cancer and their Peers: Teacher Ratings. Journal of Pediatric Psychology, 15(1):43-56, 1990.
17.Noll, R.B., LeRoy, S.S., Bukowski, W.M., Rogosch, F.A., Kulkarni, R.: Peer Relationships and Adjustments of Children with Cancer. Journal of Pediatric Psychology, 16(3):307-326, 1991.
18.Kumar, A., Gera, R., Kulkarni, R., Hogreffe, W., Kaufman, D.B.: Immunoglobulins in Hemophilia: Correlation Between IgG Subclasses, IgE and HIV Antibody. J. Clin. Lab. Immunol. 31:157-160, 1990.
19.Kumar, A., Gera, R., Kulkarni, R.: Polyfungal Systemic Infections in Pediatric Oncology Patients. The American Journal of Pediatric Hematology/Oncology 12(3): 331-335, 1990.
20.Maeda, M., Bawle, E.V., Kulkarni, R., Beutler, E., Yoshida, A.: Molecular Abnormalities of a Phosphoglycerate Kinase Variant Generated by Spontaneous Mutation. Blood 79(10):2759-2762, 1992.
21.Krivit, W.S., Freese, D., Chan, K., Kulkarni, R.: Wolman's Disease: A Review of Treatment with Bone Marrow Transplantation and Consideration for the Future. Bone Marrow Transplantation, Vol. 10, Supp. 1, 1992; 97-101. Proceedings of the Symposium on Bone Marrow Transplantation, Keystone, CO., January 13-26, 1992.
22.Noll, R.B., Bukowski, W.M., Davies, W.H., Koontz, K., Kulkarni, R.: Adjustment in the Peer System of Adolescents with Cancer: A Two-Year Study. Journal of Pediatric Psychology 18(3):351-364, 1993.
25.Davies WH, Noll RB, DeStefano L, Bukowski WM, Kulkarni R. Differences in the child-rearing practices of parents of children with cancer and controls: the perspectives of parents and professionals. J Pediatr Psychol. 1991 Jun;16(3):295-306.
26.Kumar, A., Kulkarni, R., Murray, D.L., Gera, R., Scott-Emuakpor, A.B., Bosma, K., Penner, J.A.: Serologic Markers of Viral Hepatitis A, B, C and D in Patients with Hemophilia. J. Med. Virology 41:205-209, 1993.
27.Kulkarni R. Just Say Know: Information on Parvovirus, Hepatitis and CMV. Hemophilia Update. Hemophilia Foundation of Michigan. Third/Fourth Quarter, 1994.
28.Barnes CL, Gera R, Kulkarni R. Impact of childhood cancer on patients: Caregiver reaction assessment. Supportive Care in Cancer, 4(3):241, 1996.
29.Balkundi DR., Murray DL., Patterson MJ., Gera R., Scott-Emuakpor., Kulkarni R: Penicillin resistant Streptococcus mitis as a cause of septicemia with meningitis in febrile neutropenic children. The American Journal of Pediatric Hematology/Oncology, 19(1): 82-85, 1997.
30.Thiessen B, Finlay J, Kulkarni R, Rosenblum M. Astroblastoma: Does histology predict biologic behavior? Journal of Neuro-oncology, 40(1):59-65, 1998.
31.Onyekwere OC, Hoover L, Gera R, Kulkarni R and Scott-Emuakpor AB. Sickle cell disease in children: Update for the primary care provider. Medical Update for Psychiatrists, 3:205-208, 1998.
32.Gera R and Kulkarni R. Venous Thromboembolism. Indian J Pediatr, 66:163-169, 1999.
33.Kulkarni R and Gera R. Pediatric Transfusion Therapy: Practical Considerations. Indian J Pediatr, 66:307-317, 1999.
34.Kulkarni R and Lusher JM. Intracranial and Extracranial Hemorrhages in Newborns with Hemophilia: A Review of the Literature. J Pediatr Hematol Oncol, 21(4):289-295, 1999.
35.Kulkarni R, Lusher JM, Henry RC and Kallen DJ. Current practices regarding newborn intracranial haemorrhage and obstetrical care and mode of delivery of pregnant haemophilia carriers: a survey of obstetricians, neonatologists and haematologists in the United States, on behalf of the National Hemophilia Foundation’s Medical and Scientific Advisory Council. Haemophilia. 5(6):410-415, 1999.
36.Kulkarni R. Recognize it early: Head bleeds in newborns with hemophilia. HEMAware. National Hemophilia Foundation. October 2000, pp. 44-49.
37.White GC, Aledort L., Bell W, Britton HA, Davignon GF, Ewenstein B, Ewing NP, Green D, Hanna WT, Hoots WK, Joist JH, Kessler C, Kulkarni R, Leissinger C, Luban N, Manco-Johnson M, Penner J, Seremetis SV. Treatment of Hemophilia Patients with Factor VIII inhibitors: Proceedings of a Consensus panel. A CME program by Nabi pharmaceuticals May 2001, pages 6-16.
38.Kulkarni R, Scott-Emuakpor AB, Brody H, Ragni MV, Weil WB, Gera R, Bosma K, Penner JA, and the Center for Ethics and Humanities in the Life Sciences at Michigan State University. Nondisclosure of HIV/HCV in a Co-infected hemophilic male: medical and ethical dilemma. Journal of Pediatric Hematology/Oncology 2001; 23:153-158.
39.Kulkarni R and Lusher J. Perinatal management of newborns with haemophilia. British Journal of Haematology 112:264-274, 2001.
40.Kulkarni R. Bleeding in the Newborn. Pediatric Annals 30:548-556, 2001.
41.Kulkarni R, Aledort LM, Berntorp E, Brackman HH, Brown D, Cohen AR, Ewing NP, Gringeri A, Gruppo R, Hoots K, Leissenger C, Peerlinck K, Poon MC, Wong WY. Therapeutic choices for patients with haemophilia and high titre inhibitors. American Journal of Hematology 67:240-246, 2001.
42.Robbins D, Kulkarni R, Gera R, Scott-Emuakpor AB, Bosma K, Penner JA. Successful Treatment of High Titer Inhibitors in Mild Hemophilia A with Avoidance of Factor VIII and Immunosuppressive Therapy. American Journal of Hematology 68:184-188, 2001.
43.Kulkarni R, J. Wolf JS, Padiyar N, Zuckerman L, Gera R, Scott-Emuakpor AB. Severe intrarenal fibrosis, infundibular stenosis, renal cysts and persistent nephrogenic rests, in a patient with Beckwith Wiedemann syndrome 27 years following diffuse nephroblastomatosis (DNB) and Wilms tumor (WT): Natural progression or a consequence of treatment? Accepted by Journal of Pediatric Hematology/Oncology. 2002 Jun-Jul;24(5):389-93.
44.S. Arkin,1 L.M. Aledort,2 D. Brown,3 R. Gruppo,4 K. Hoots,5 R. Kulkarni,6 E. Santagostino,7 P. Schroth,8 G.L. Bray,8 and the Recombinate Study Group. Bleed Patterns and Frequencies: The Natural History of Infants and Young Children with Hemophilia A, a Multi-Center Experience. Submitted to Blood, 2001.
45.White paper for research priorities. Neonatal task force. National Hemophilia Foundation.
46.Bussel JB, Eldor A, Kelton JG, Varon D, Brenner B, Gillis S, Angiolillo A, Kulkarni R, Abshire TC. IGIV-C a novel intravenous immunoglobulin: evaluation of safety, efficacy, mechanisms of action and impact on quality of life. Submitted to the British Journal of Haematology.
47.Olomu N, Kulkarni R, Manco-Johnson M. Treatment of severe pulmonary hemorrhage with activated recombinant factor VII (rFVIIa) in very low birth weight infants: case reports. Journal of Perinatology 2002; 22 (8), 672-674.
48.Vyas H, Scott-Emuakpor A, Kulkarni R, Gera R. Acute Leukemias in Children. Submitted to the Indian Journal of Pediatrics.
49.Kulkarni R, Daneshmand A, Guertin S, Fath J, Atwal J, Melvin J, LaFrance Successful use of recombinant factor VIIa (rFVIIa) in traumatic liver injuries in children. Accepted by Journal of Trauma.
50.Kulkarni R, Soucie MJ, Evatt B. Prevalence and risk factors for renal disease among males with hemophilia. (In preparation).
51.Kulkarni R, Soucie MJ, Evatt B. Prevalence and risk factors for heart disease among males with hemophilia. (In preparation).
Published Abstracts (*denotes oral presentation; **denotes poster presentation):
1.*Rapid Diagnosis of Meningitis Using Cytocentrifugation Technique. Kulkarni, R., Leader, I., Murray, D. Society of Pediatric Research, 1982.
2.*Familial Occurrence of Cryptorchidism and Testicular Tumors in Non-Twin Brothers. Kulkarni, R., Netzloff, M, Texeira, C. Society for Pediatric Research, 1982.
3.A Canine Neonate Model for the Study of Granulocyte Transfusion in Septicemia. Kulkarni, R., Karna, P., Coffman, P., Bull, R. Society of Pediatric Research, 1982.
4.Immunological Evaluation of Patients with Hemophilia. Gera, R., Jin, Z., Cleveland, R., Murray, D., Kulkarni, R., Romond, E., Kaufman, D.B.. Society for Pediatric Research, May 1984.
5.Unique Chromosome Abnormality in a Child with Pre B Cell Leukemia. Cousineau, A.J., Gera, R., Kulkarni, R. Society for Pediatric Research, 1984.
6.Tryptophan Pyrrolase Activity and Elevated Brain 5-HT in Iron Deficient Rats: A Mechanism for Behavioral Changes. Kulkarni, R., Gera, R., Draznin, M., Parker, L. American Society of Hematology, 1985.
7.A New Infantile Acute Leukemia with a Unique Chromosomal t(4;11) Rearrangement. O'Malley, D.P., Kulkarni, R., Higgins, J.V. Pediatric Research, April, 1985.
8.*Role of Gap Junctional Intercellular Communication in the Regulation of Growth and Differentiation of Normal and Malignant Human Epithelial Cells. Trosko, J.E., Chang, C.C., El-Fouly, M.H., Kulkarni, R., Gera, R. Fourth Decennial Review --- Cell and Tissue Culture International Conference, September 22-26, 1986.
9.*Inhibition of Intercellular communication in Human Carcinoma Cell Lines of Various Origins as Determined by Three Newly Developed Methods. Gera, R., Kulkarni, R., El-Fouly, M.H., Chang, C.C., Trosko, J.E. American Association for Cancer Research, 1987.
10.A Platelet Aggregation Factor in Plasma from Sickle Cell Disease. Turner, E., Bolenbaugh, J.G., Gera. R., Kulkarni, R. American Society for Hematology. 1987.
11.Central Venous Catheter Infections in Pediatric Patients in a Community Hospital. Kumar, A., Brar, S.S., Murray, D.L., Leader, I., Gera, R., Kulkarni, R. Society for Pediatric Research, vol. 23, April 1988.
12.Reinduction Chemotherapy for Children with Acute Lymphoblastic Leukemia in Relapse. Gera, R., Scott-Emuakpor, A., Noll, R.B., Kulkarni, R. American Society of Hematology, 1989.
13.*Mechanisms of Adriamycin-resistance of human breast cancer cell line, MCF-7. Kulkarni, R., Madhukar, B.V., Jou, Y.S., Jiwa, Y., Chang, C.C., Charmella, L., Trosko, J.E., Dimitrov, N. American Cancer Society, 1991 Cancer Research Conference, Detroit, MI, September 20, 1991.
14.A comprehensive study of antibody status in patients with hemophilia. Kulkarni, R., Kumar, A, Penner, J.A., Murray, D., Anderson, G, Gera, R., Scott-Emuakpor, A.B. Blood 76(10):426a, 1990.
15.**Should children with cancer avoid school and crowded places during periods of treatment realted neutropenia? Results of a survey. Gera, R., Kulkarni, R., Scott-Emuakpor, A.B. The American Society of Pediatric Hematology/Oncology, Fourth Annual Meeting Scientific Proceedings, page 26, September 12-14, 1991.
16.**Antibody Status in Patients with Hemophilia - A Comprehensive Study. Kulkarni, R., Kumar, A., Murray, D., Anderson, G., Gera, R., Scott-Emuakpor, A.B., Bosma, K., Penner, J.A. National Hemophilia Foundation 43rd Annual Meeting, Tampa, October 8-12, 1991.
17.**Serologic Markers of Viral Hepatitis A, B, C and D in Patients with Hemophilia. Kumar, A., Kulkarni, R., Murray, D.L., Gera, R., Scott-Emuakpor, A.B., Bosma, K., Penner, J.A. National Hemophilia Foundation 43rd Annual Meeting, Tampa, October 8-12, 1991.
18.**Successful Treatment of Thrombocytopenia with Intravenous Immunoglobulin (IV IgG) During Induction (I) and Consolidation (C) Phase of all in a Patient (PT) with Underlying ITP. Gera, R., Kulkarni, R., Scott-Emuakpor, A. The American Society of Pediatric Hematology/Oncology, Fifth Annual Meeting Scientific Proceedings, page 33, September 24-26, 1992.
19.*Increased Retention of Adriamycin by a Protein Kinase C Inhibitor, Calphostin C in Resistant MCF-7 Human breast Tumor Cells. R. Kulkarni, B.V. Madhukar, H. Rupp, C. Chang, J.E. Trosko, L. Charmella, N. Dimitrov. Proceedings of the American Association of Cancer Research, volume 33, page 438, March 1992.
20.**HIV Infection Associated with Urinary Tract Infection (UTI) in Hemophiliacs. Scott-Emuakpor, A.B., Gera, R., Kulkarni, R., Kumar, A., and Bosma, K. Scientific Proceedings of the American Society of Pediatric Hematology/Oncology, page 32, September 1992.
21.**Thrombocytosis in the Newborns. Gera, R., Tam Su, A., Kulkarni, R., Lorenz, J. Scientific Proceedings of the American Society of Pediatric Hematology/Oncology, page 28, September 1993.
22.**Vaccination Responses of Patients with Hemophilia. Kulkarni, R., Gera, R., Kumar, A., Murray, D., Scott-Emuakpor, A.B., Anderson, G., Downs, F.P., Bosma, K., and Penner, J.A. Scientific Proceedings of the American Society of Pediatric Hematology/Oncology, page 28, September 1993.
23.**A Time and Cost Analysis of Patient Provided versus Hospital Provided Clotting Factor Concentrates for Outpatient Treatment of Hemophilia in a Community Hospital. M. Kalyanaraman, R. Kulkarni, R. Gera, A.B. Scott-Emuakpor, K.Bosma, S. Jensen, J.A. Penner. National Hemophilia Foundation Annual Meeting, October 1994.
24.**Totally Implantable Subcutaneous Ports for Long Term Venous Access in patients with Various Bleeding Disorders. R. Gera, R. Kulkarni, A.B. Scott-Emuakpor, K. Bosma, J.A. Penner. National Hemophilia Foundation Annual Meeting, October 1994. Published as a selected abstract in Transfusion 35(5):440, 1995.
25.Viral Safety of an Affinity Purified Coagulation Factor IX Concentrate (Alphanine,SD). D Becton, C Manno, D Green, G Gilchrist, R Kulkarni, J Priest, C Sexauer, W Schlueter and F Norton. Blood, 1994
26.**Chronic bone marrow failure syndrome with Myelodysplasia in two adopted Korean children. R. Gera, R. Kulkarni and A.B Scott-Emuakpor. ASPHO. 1995
27.**Penicillin resistant streptococcus mitis (Sm) meningitis in febrile neutropenic children (FNC). R Gera, D Balkundi, MJ Patterson, AB Scott-Emaukapor, DL Murray, R Kulkarni. ASPHO. 1995.
28.Viral safety of an affinity-purified coagulation Factor IX concentrate (Alpha Nine SD). D Becton, C Manno, M Heisel, D Beardsley, D Green, G Gilchrist, R Kulkarni, T Loew, J Priest, C Sexauer, W Schlueter, R Nuss and F Norton. XXII International Congress of the World Federation of Hemophilia, Dublin , Ireland June 1996.
29.**Impact of childhood cancer on parents: Caregiver reaction assessment. C.L. Barnes, R. Gera and R. Kulkarni. Poster presentation at the MASCC Eighth International Symposium on supportive care in cancer. Toronto, Canada. June 1996.
30.**Microcytic Hypochromic Anemia (MHA) and Lymphoblastic Lymphoma/Acute Lymphoblastic Leukemia. R. Gera, R. Kulkarni and A.B. Scott-Emuakpor. The American Society of Pediatric Hematology/Oncology. Chicago, Sept.10-12, 1996.
31.**Childhood Cancer Care: Feelings of Depression in parents. C.L. Barnes R. Gera, R. Kulkarni and A.B. Scott-Emuakpor. The American Society of Pediatric Hematology/Oncology. Chicago, Sept.10-12, 1996.
32.**Cancer Care in Children: Parents’ Perception of Financial Burdens. R. Gera, C.L. Barnes , R. Kulkarni and A.B. Scott-Emuakpor. The American Society of Pediatric Hematology/Oncology. Chicago, Sept.10-12, 1996.
33.**Transient magnetic resonance imaging (MRI) changes in central nervous system (CNS) following seizures in patients with acute lymphoblastic leukemia (ALL): Ischemia or postictal change? R. Gera, R. Kulkarni and A.B. Scott-Emuakpor. The American Society of Pediatric Hematology/Oncology. San Francisco, Sept.1997.
34.**Neurologic sequelae of intrathecal methotrexate: a case of severe debilitating leukoencephalopathy. R. Gera, R. Noll and R. Kulkarni. The American Society of Pediatric Hematology/Oncology. San Francisco, Sept.1997.
35.*Neonatal intracranial hemorrhage and obstetrical care and mode of delivery of pregnant hemophilia carriers: A survey of obstetricians, neonatologists and hematologists in the United States. Kulkarni R, Lusher JM, Henry RC and Kallen DJ. XXIII International Congress of the World Federation of Hemophilia. The Netherlands Congress Centre. The Hague. May 18,1998.
36.**A review of cranial hemorrhages in neonatal hemophilia. Kulkarni R and Lusher JM. XXIII International Congress of the World Federation of Hemophilia. The Netherlands Congress Centre. The Hague. May 18, 1998.
37.**Long term intranasal desmopressin acetate prophylaxis and avoidance of factor VIII concentrates (FVIIIc) in mild hemophilia a (mha) with high titer inhibitors (HTI). Robbins D*, Kulkarni R, Gera R, Scott-Emuakpor A, Bosma K and Penner JA, Michigan State University, East Lansing, MI, USA. XVIIth Congress of the International Society of Thrombosis and Haemostasis. Washington D.C. Aug 17, 1999.
38.**Nondisclosure of HV/HCV in a Co-infected hemophilic male: medical and ethical dilemma. Kulkarni R, Scott-Emuakpor AB, Brody H, *Ragni MV, Weil WB, Gera R, Bosma K, Penner, JA, and the Center for Ethics and Humanities in the Life Sciences, Michigan State University, East Lansing, MI, USA and *University of Pittsburgh, PA, USA. 1999 Joint Annual meeting of the International Society of Pediatric Oncology and the American Society of Pediatric Hematology/Oncology. Montreal CA. Sept. 17. 1999
39.Primary orbital lymphoma in children: A report of two unusual cases. Elliott M, Kulkarni R, Gera R, Scott-Emuakpor AB, Padiyar N, Cavanaugh E, Rice C, Hoover L, Patterson MJ, Michigan State University, East Lansing, MI, USA. J. Pediatr Hematol Oncol 21(4):313, Abstract No. 196, 1999.
40.**Fatal hyperkalemia during surgery for Burkitt’s lymphoma (Bl). Gera R, Scott-Emuakpor AB, Kulkarni R, Greenfeld J, Lelli J, Michigan State University, East Lansing, MI, USA and University of Michigan, Ann Arbor, MI, USA. J Pediatr Hematol Oncol 21(4): 313, Abstract No. 194, 1999.
41.**ADHD in 6-14 year old hemophilia population pilot study. Merritt D, McGinty L, Palazzolo V, Adkins S, Bosma K, Munn J, Gera R, Kulkarni R, Pipe S, Warrier I. National Hemophilia Foundation 52nd Annual meeting CA 2000.
42.*ADHD in 6-14 year old hemophilia population pilot study. Merritt D, McGinty L, Palazzolo V, Adkins S, Bosma K, Munn J, Gera R, Kulkarni R, Pipe S, Warrier I. World Federation of Haemophilia, July 2000, Montreal
43.**Long term intranasal desmopressin acetate prophylaxis and avoidance of factor VIII concentrates (FVIIIc) in mild hemophilia a (mha) with high titer inhibitors (hti). Robbins D*, Kulkarni R, Gera R, Scott-Emuakpor A, Bosma K and Penner JA, Michigan State University, East Lansing, MI, USA. July 17, 2000 World Federation of Haemophilia, July 2000, Montreal.
44.**Nondisclosure of HIV/HCV in a co-infected hemophilic male: medical and ethical dilemma. Kulkarni R, Scott-Emuakpor AB, Brody H, *Ragni MV, Weil WB, Gera R, Bosma K, Penner, JA, and the Center for Ethics and Humanities in the Life Sciences, Michigan State University, East Lansing, MI, USA and *University of Pittsburgh, PA, USA. July 19, 2000 World Federation of Haemophilia, July 2000, Montreal.
45.**A 27 year follow up of persistent nephrogenic rests (NR), diffuse nephroblastomatosis (DNB) and Wilms tumor (WT) presenting with severe intrarenal fibrosis, infundibular stenosis and cystic renal dysplasia: natural progression or a consequence of treatment? Kulkarni R, Wolf Jr. JS, Padiyar N, Zuckerman L, Gera R, Scott-Emuakpor AB, and Cavanaugh E. American Society of Pediatric Hematology/Oncology, September 2000.
46.**Transient acute renal failure (ARF) and intravascular hemolysis (IVH) following intravenous (IV) anti-D treatment of immune thrombocytopenia (ITP). Gera R, Kulkarni R, Scott-Emuakpor AB. Michigan State University, Pediatrics/Human Development, East Lansing, MI. American Society of Pediatric Hematology/Oncology, September, 2000.
47.*Safety and efficacy of a novel IGIV preparation in the treatment of ITP. Bussel J. Eldor A, Liat N, Kelton J, Varon D, Angiolilo A, Brenner B, Abshire T, Gillis S, Kulkarni R, Lemm G and the ITP Study Group. ISTH July 2000.
48.**Rapidly advancing proptosis in a four-year old child with HIV infection. Patterson MN, Elliott M, Kulkarni R, Gera, R. Fifth International AIDS Malignancy Conference, Bethesda, 2001.
49.**Olomu N, Kulkarni R, Manco- Johnson M. Treatment of intrapulmonary hemorrhage with activated recombinant Factor VII (rFVIIa) in very low birth weight (VLBW) infants on mechanical ventilation in a community level III neonatal intensive care unit (NICU). Presented as a poster American Society of Hematology 2001. Blood 2001;98: 262A-263A.
50.Kulkarni R, Daneshmand A, Guertin S, Fath J, Atwal J, Melvin J, LaFrance Successful use of recombinant factor VIIa (rFVIIa) in traumatic liver injuries in children. Poster Presented at the American Society of Pediatric Hematology/Oncology, Baltimore. May 5, 2002.
51.Kulkarni R, Daneshmand A, Guertin S, Fath J, Atwal J, Melvin J, LaFrance Successful use of recombinant factor VIIa (rFVIIa) in traumatic liver injuries in children. World Federation of Hemophilia, Seville Spain, May 20, 2002. Published in Hemophilia, 2002, 8, page 492.
52.ADHD in 6-14 year old hemophilia population pilot study. Merritt D, McGinty L, Palazzolo V, Adkins S, Bosma K, Munn J, Gera R, Kulkarni R, Pipe S, Warrier I. World Federation of Haemophilia, Seville Spain May 2002. Published in Hemophilia, 2002, 8, page 492.
53.Kulkarni R, Soucie M, Evatt BL and the Hemophilia Surveillance System Project Investigators. Renal disease among males with hemophilia. Presented poster at the American Society of Hematology meeting, Philadelphia 2002. Abstract No. 1919. Blood 2002;100 (11): 493a.
54.Kulkarni R, Reddy UM, Evatt BL. How does blood clot?Physiology of hemostasis: Clotting pathways, platelets, endothelium, and cell based coagulation: A novel teaching tool using computer based animation. Blood 2002;100 (11): 501b.
55.Gera R, Kulkarni R, Scott-Emuakpor AB, Netzloff M. Carnitine replacement for symptomatic hypoglycemia in a patient with Acute Lymphoblastic Leukemia.. Submitted to American Society of Pediatric Hematology/Oncology, May, 2003.
56.Gera R, Gulnar C, Scott-Emuakpor AB, Kulkarni R. Vasoocclusive crises in sickle hemoglobin E (SE) disease. Submitted to American Society of Pediatric Hematology/Oncology, May, 2003.
57.Kulkarni R, Soucie M, Evatt BL and the Hemophilia Surveillance System Project Investigators. Renal disease among males with hemophilia. Submitted to the International Society of Thrombosis and Hemostasis 2003.
58.Kulkarni R, Soucie M, Evatt BL and the Hemophilia Surveillance System Project Investigators. Heart disease among males with hemophilia. Submitted to the International Society of Thrombosis and Hemostasis 2003.
Workshop Invited to present a workshop on “How to develop and use animations and digital collaboration as teaching tools: New horizons in teaching generation X” at the Pediatric Academic Societies meetings, Seattle WA 2003.
Text book chapters:
1.Lusher J and Kulkarni R. Hereditary and acquired coagulation disorders. Chapter 11. Transfusion medicine in practice. Editors: Duguid J, Goodnough LT, Desmond MJ. Martin Dunitz publishers, London U.K. 2002.
2.Gera R, Kulkarni R. Venous Thromboembolism. IN S. Gupta (ed.), RECENT ADVANCES IN PEDIATRICS. Special Volume 8, Emergency Medicine, pp. 230-238, 2001, Jaypee Brothers Medical Publishers LTD, New Delhi.
3.Kulkarni, R., Gera, R., Penner, J.A.: Hemophilia and Other Inherited Coagulation Disorders IN Rex B. Conn (ed), CURRENT DIAGNOSIS 605-611, 1991, W.B. Saunders Company.
4.R. Gera, R. Kulkarni, A.B. Scott-Emuakpor: Hemorrhage, Shock and Disseminated Intravascular Coagulopathy IN Donnellan, W.L., Kimura, K, and Soper, R.T. (eds.), ABDOMINAL SURGERY OF INFANCY AND CHILDHOOD, pp.4/1 - 4/17, 1996, Harwood Academic Publishers.
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